The Version-4 Focused on Awake Resting-state Functional Connectivity
Abstract Comprehensive integration of the structural and functional connectivity data is a requirement for accurate modeling of brain functions. While resources for charting the marmoset structural connectivity already exist, open data and tools for functional brain mapping are still unavailable. Here, we present the most comprehensive resource for non-human primate brain mapping, which integrates the largest awake resting-state test-retest fMRI dataset (39 marmosets, 709 runs, and 12053 mins), cellular-level neuronal-tracing dataset (52 marmosets, and 143 injections), and multi-resolution diffusion MRI dataset. The combination of these data into the same stereotaxic space allowed us: 1) mapping the fine-detailed functional networks and cortical parcellations; 2) developing a deep-learning-based parcellation generator to preserve the topographical organization of functional connectivity and reflect individual variabilities; 3) investigating the structural basis underlying functional connectivity by computational modeling. Therefore, our resource will broadly model the marmoset brain architecture and facilitate future comparative and translational studies of primate brains.